This study presents a valuable comparison of the efficiency and precision of two prime editing methods to introduce single-nucleotide variants and longer exogenous DNA sequences into the zebrafish ...

The efficiencies with which activated B lymphocytes proliferate and develop into antibody (Ab)- secreting plasma cells are critical determinants of adaptive humoral immunity and central to sustaining ...

This important study reports an advancement in the diagnosis of Animal African Trypanosomosis (AAT), which adapts a CRISPR-based diagnostic tool (SHERLOCK4AAT) to detect different trypanosome species ...

The study presents valuable theoretical insights by attempting to classify pattern-forming gene subnetworks and exploring their potential mechanisms. However, the results are incomplete, as they rely ...

Immunology and Inflammation Xcr1 + type 1 conventional dendritic cells are essential mediators for atherosclerosis progression ...

In this episode, we hear about parasites as molecular matchmakers, drug combinations and cancer treatment, chemical defences in poison frogs, the impact of education on brain structure, and what ...

Altmetric provides a collated score for online attention across various platforms and media. See more details Flat clathrin lattices accumulate in cells depleted of CCDC32. (A-B) Representative PREM ...

Reviewer #1 (Public review): Summary: The authors developed SHERLOCK4AAT, a CRISPR-Cas13a-based diagnostic toolbox for detecting multiple trypanosome species responsible for animal African ...

Reviewer #2 (Public review): The chemoreceptor proteins expressed by olfactory sensory neuron differ in their selectivity such that glomeruli vary in the breadth of volatile chemicals to which they ...

Pan and species-specific SHERLOCK assays for human and animal African trypanosome infections. Supplementary Figure 1. A: Representation of the proportions of identity between 18S rRNA (A) and GAPDH (B ...

Time-resolved fluorescence resonance energy transfer reveals conformational energetics of a bacterial cyclic nucleotide-gated ion channel.

There is a striking correspondence between face-selective neural increases vs decreases of fMRI BOLD signal and spikes in neighboring human fusiform gyrus regions.