The good news for the 49ers backfield is that running back Christian McCaffrey is healthy. The bad news is that most of the other backs on the roster are not. Isaac Guerendo and fifth-round pick Jordan James missed the game with injuries and wo more running backs went down during the contest.

The San Francisco 49ers saw three players go down with injuries on Saturday. Here's what Kyle Shanahan said after the game.

Now that the San Francisco 49ers have played two preseason games, the 53-man roster projection is starting to become a bit clearer. Where does the roster stand with one game to go? Carter Bradley made a case for the practice squad, but that still may not be the case.

Kiner was carted off the field during the second quarter of Saturday's preseason game against the Raiders due to a left leg injury, Jennifer Lee Chan of NBC Sports Bay Area reports.

The San Francisco 49ers on Saturday secured their first win of the preseason with a thrilling 22-19 win over the Las Vegas Raiders. That victory also catalyzed a new 53-man roster projection.

RG Dominick Puni suffered a PCL injury and is uncertain to be ready for Week 1. RBs Patrick Taylor, Corey Kiner also hurt.

The injury-riddled 49ers do have some players worth watching in Saturday’s preseason visit to the Raiders after possible cameos by select starters.

Through just two preseason games, the 49ers already have four injured running backs -- Isaac Guerendo (shoulder), Patrick Taylor Jr. (shoulder), Jordan James (finger) and Corey Kiner (ankle). Their only healthy running backs currently are Christian McCaffrey, Jeff Wilson Jr. and Ke'Shawn Vaughn.

Kiner suffered a left high-ankle sprain in Saturday's preseason game versus Las Vegas, Eric Branch of the San Francisco Chronicle reports.

An undrafted rookie running back caught Kyle Shanahan's eye, and Marques Sigle's ascent at safety is putting pressure on two veterans.